S. pyogenes is a very important human pathogen. It is the major cause of strep throat. Scarlet fever is  also caused by S. pyogenes strains that produce erythrogenic toxin. Some strains  of this microorganism are the infamous flesh-eating bacteria. They produce necrotizing enzymes that cause rapid and extensive destruction of tissue—a condition which is known as necrotizing fasciitis. The toxic shock disease caused by S. pyogenes is technically called toxic shock–like syndrome (TSLS) and is caused by a toxin that is somewhat similar to the TSST-1 produced by S. aureus. However, the TSLS toxin is different. It is called streptoccocal pyrogenic toxin (Spe). S. pyogenes has not developed resistance to penicillin, so penicillin remains the drug … Continue reading